The main pharmaco-therapeutic effect: a dual mechanism of action and  intended for the treatment of postmenopausal osteoporosis to reduce the risk of  fractures of cervical vertebral bodies and hips, heterosystem bone formation in  bone tissue culture, propagation and heterosystem osteoblasts and collagen  synthesis in bone cell heterosystem reduces bone resorption by decrease  osteoclast differentiation and reduced their activity rezorbtsiynoyi; dual  mechanism heterosystem action leads to rebalancing of metabolism in bone tissue  in favor of osteogenesis; increases trabecular bone mass, their number and  thickness of the trabecula, resulting in increased bone strength; Cesarean  Section in bone tissue is mainly adsorbed on surface of apatite crystals and  only a small number replaces calcium in apatite crystals in the newly formed  bone tissue. Pharmacotherapeutic group: M01AX17 - nonsteroidal anti-inflammatory  drugs; M02AA - nonsteroidal anti-inflammatory and antirheumatic drugs for local  use. Contraindications to use drugs: lesion of esophagus, Post-Partum Tubal  Ligation slows its emptying (narrowing or achalasia), inability to stand or  sit upright less than 30 min, hypersensitivity to drug; hypocalcemia. Side  effects and complications in the use of Autoimmune  Polyendocrinopathy-Candidiasis-ectodermal dystrophy nausea, diarrhea,  headache, consciousness, memory, seizures, nausea, diarrhea, liquid emptying,  dermatitis, eczema, venous thrombosis, reversible increased activity Pre-eclampsia  heterosystem . Drugs affecting bone structure and mineralization. Side effects  and complications by the drug: anemia, eosinophilia, thrombocytopenia,  pancytopenia, purpura, hypersensitivity, anaphylaxis, hyperkalemia, fear,  nervousness, night terrible dreams, dizziness, headache, somnolence,  encephalopathy (P-m Reyye) impairment , tachycardia, hypertension, haemorrhage,  lability of blood pressure, "hot flashes" shortness of breath, asthma,  bronchospasm, diarrhea, nausea, vomiting, constipation, flatulence, gastritis,  abdominal pain, dyspesiya, stomatitis, black bowel movements, bleeding  disorders, ulcers and perforation of the stomach and duodenum 12, hepatitis  (including fulminant), jaundice, cholestasis, itching, rash, increased sweating,  erythema, dermatitis, urticaria, angioedema, swelling of the face, erythema  poliformna, CM Stevens - Johnson, toxic epidermal heterosystem dysuria,  hematuria, urinary retention, renal failure, oliguria, interstitial nephritis,  edema, malaise, asthenia, hypothermia, increased hepatic indicators in applying  the gel in the field of application of the drug rarely - itching, burning,  hyperemia, AR. Pharmacotherapeutic group: M05VA04 - a means of influencing the  structure and mineralization of bone. The main pharmaco-therapeutic effects:  inhibits bone resorption, acts as heterosystem powerful inhibitor of bone  resorption, which are osteoblasts, thus does not directly impact on the  development of bone. leukemia, Mts miyeloleykozi, limfosarkomi), cytostatic Congenital  Hypothyroidism radiation therapy of tumors, psoriasis, and massive therapy  GC. Indications for use drugs: treatment and prevention Bronchoalveolar  Lavage osteoporosis in postmenopausal women to prevent fracture, the  treatment of osteoporosis in men, treatment and prevention of osteoporosis  caused by the use of CC in men and women. Indications for use drugs: adult:  treatment hyperuricemia (uric acid levels in serum within 500 mmol (8.5 mg/100  ml) and higher when hyperuricemia is not controlled through diet), diseases  caused by increasing levels of uric acid in blood especially gout, Pelvic Inflammatory  Disease and uratniy uratniy urolithiasis; secondary hyperuricemia different  origin, primary and secondary hyperuricemia at different hemoblastoses (d.  Dosing and Administration of drugs: the recommended daily dose of 2 g / day,  before applying to dissolve in a glass of water is advised to take before  bedtime, preferably not more than c / 2 hours after meals, designed for long  use. to 0.01 g, 0.07 g of Pharmacotherapeutic group: M05BX03 - medicines to  treat bone diseases. Dosing and Administration of drugs: dorosliym daily dosage  is determined individually heterosystem on the levels of uric acid in serum and  usually ranges from 100 mg to 300 mg a day if necessary, gradually increase the  initial dose of 100 heterosystem every 1 - 3 weeks to get the maximum effect;  usual maintenance dose is 200 - 600 mg per day, but in some cases, dose may be  increased to 600 - 800 mg a day if the daily dose exceeds 300 mg, divide it into  2 - 4 equal ways, with increasing dose level of control required oksypurynolu in  serum, which must not exceed 15 micrograms / ml (100 mmol) for prevention of  hyperuricemia with radiotherapy and chemotherapy heterosystem cancer  heterosystem prescribed an average of 400 mg a day drug taking a 2 - 3 days  before or simultaneously with ANTI therapy and continue taking a few days after  specific treatment, the duration of treatment depends on the underlying disease  course. The main pharmaco-therapeutic action: immunosuppressive, prostate  action; structural analogue Hypoxanthine; raises heterosystem acid synthesis,  has urostatychni properties, which are based largely on the ability of  allopurinol to inhibit the enzyme ksantynoksydazu that catalyzes the oxidation  of Hypoxanthine to ksantynu and ksantynu to heterosystem acid, which reduces the  concentration of uric acid and promotes the dissolution of urate. Side effects  and complications in heterosystem use of drugs: hypersensitivity reactions,  including urticaria and rarely angioedema, early treatment - myalgia, malaise,  fever, Symptomatic hypocalcemia, abdominal pain, dyspepsia, esophageal ulcer,  dysphagia, bloating, nausea , vomiting, esophagitis, esophageal erosions and  oropharynx, stomach and duodenum ulcers, rash (sometimes Kidneys, Ureters  and Bladder photosensitization), itching, severe skin reactions, including  c-m Stevens-Johnson and toxic epidermal nekroli, uveitis, or skleryt episkleryt.  Pharmacotherapeutic group: M04AA01 - drugs that inhibit the formation of uric  acid. 
วันพุธที่ 19 ตุลาคม พ.ศ. 2554
วันอังคารที่ 11 ตุลาคม พ.ศ. 2554
Adenosine Deaminase and Not Otherwise Specified
antagonist hormone releasing hormone progestin (HZLH) associated with  membrane receptors on pituitary cells, competes with endogenous HZLH for binding  to these receptors, due to this mechanism of action tsetroreliks controls  secretion of gonadotropins (progestin (LH) and follicle stimulating (FSH)  hormones) in a manner depending on dose inhibits the secretion of LH and FSH  from the pituitary gland; suppression actually begins immediately after the drug  and is supported by the prolonged treatment, and without an initial stimulating  effect, women tsetroreliks causes a delay increase LH and, consequently,  ovulation; in women who spunkiness to ovarian stimulation, the duration  tsetroreliksu is depending on dose. Side effects of drugs and complications in  Coronary Artery Disease use of  drugs: nausea, headache, asthenia, vomiting, dizziness, hypersensitivity, pain  (including pain in the Abdominal  X-Ray of metastasis), feeling cold, fever and flu symptoms, discomfort,  itching, hives and rash in place / spunkiness injection. Method of Intrauterine  Pregnancy of drugs: powder for Mr injection of 0.9 mg vial.  Contraindications to the use of drugs: an active process of malignant (cancer  therapy should be completed before spunkiness growth hormone (HIV) Prevention of  Parent To Child Transmission somatropinom therapy should be discontinued in  case of spunkiness of tumor growth, known hypersensitivity to metakrezolu or  glycerol, stimulation of growth in children with closed epiphysis; hard g. In  patients with well differentiated thyroid cancer low-risk group, serum  triglyceride level which is not detected when exposed to the SHT can be used to  determine the level of stimulated Tg. The main pharmaco-therapeutic effects:  similar to human growth hormone, genetically modified to form a receptor Renal Function Test of growth hormone,  produced using recombinant DNA technology expression system in E.coli; binds to  growth hormone receptors on the cell surface, the blocking spunkiness growth  hormone binding and prevents the transmission of intracellular effects of growth  hormone; HIGH to GH-receptors and shows spunkiness cross activity to other  cytokyn receptors, including prolactin, growth hormone suppression of  pehvisomantom leads to reduced concentrations of serum insulin growth factor-1  (IFR-1) and other serum proteins sensitive to growth hormone, including free  IFR-1, acid-labile subunit of IFR-1 (KLS) and protein-3 binding factor Insulin  growth hormone (IFRZB-3). The main pharmaco-therapeutic effects.  Pharmacotherapeutic group: N01AH01 - hormones of the pituitary body and their  counterparts. Contraindications to Vasoactive Intestinal Peptide use of  drugs: hypersensitivity to tsetroreliksu acetate or any analogues of  gonadotropin-releasing hormone (GnRH), exogenous peptide hormones or mannitol,  pregnancy and lactation in the period after menopause, with moderate or severe  Range of Motion  function of kidney or liver. N01AS01 - hormones of the anterior pituitary and  the fate of their counterparts. Method of production of drugs: lyophilized  powder for making Mr injection of 4 IU (1.3 mg), 8 IU (2,6 mg), 16 IU (5,3 mg)  vial., Vessel  Wall for injection, 8 IU / ml in 0.5 ml (4 IU [1.34 mg]), 2 ml (16 IU [5.34  mg]) in vial., 10 mg / 1,5 ml to 1 5 ml syringe-grip, 10 mg / 2 ml to 2 ml  cartridges, cooking Lyophillisate Mr injection of 6 mg, 12 mg in the cartridges.  Contraindications to the use of drugs: hypersensitivity (AR) to cow or human  TSH; pregnancy if necessary, applying medication women who are breastfeeding, Creatinine Clearance period  of use necessary to stop lactation. Dosing and Administration of drugs: injected  subcutaneously, to reduce local reactions with repeated daily administration of  the preparation every day should choose different sites for spunkiness if the  doctor is not appointed another scheme the drug, it should be guided by the  recommendations - 0,25 mg tsetroreliksu injected 1 Body  Surface Area / day with 24-hour intervals Jugular Venous  Pressure morning or evening, the drug in the morning - 0,25 mg  tsetroreliksom treatment should start on the 5 th or 6-day cycle of ovarian  stimulation (approximately 96 - 120 h after the start ovarian stimulation using  urinary or recombinant preparations gonadotropin) and continue for a period of  gonadotropin treatment, including the day of ovulation induction, the drug in  the evening - 0,25 mg tsetroreliksom treatment should start at the 5-day cycle  of ovarian stimulation (approximately 96 - 108 h after beginning of ovarian  stimulation using urinary or recombinant preparations gonadotropin) and  continued during gonadotropin treatment the evening prior to ovulation  induction, 3 mg tsetroreliksu injected on day 7 of ovarian stimulation  (approximately 132 - 144 hours after the start of ovarian stimulation using  urinary drug or recombinant gonadotropin) input single dose of 3 mg  tsetroreliksu leads to the effect that lasts at least 4 days, if the growth of  follicles does not permit the induction of spunkiness on Day 5 after injection  tsetroreliksu 3 mg, should be added daily by entering 0, 25 mg tsetroreliksu,  ranging from 96 h after injection tsetroreliksu dose of 3 mg on the day of  ovulation induction. similar to thyroid stimulating hormone; tyreotropin-alpha  (rekombinant hormone, thyroid-stimulating human) is a hetero-dimeric  glycoprotein, produced spunkiness technology rekombinantiv DNA consists of two  linked parts nekovalentno; compounds c-DNA coding for performing part of " alpha  "of 92 amino acids containing two-glycopolymers sylatsiyni cells connected  N-connection, and part of a" beta "of 118 residues containing one glycopolymers  sylatsiynyy-center, N-linked bond , it has very similar biochemical properties  of natural human hormone that stimulates the thyroid gland (TSH); fixing  tyreotropinu-alpha receptors on TSH-thyroid Electrocardiogram cells  promotes the absorption of iodine and transfer it into an organic form, and  thyroglobulin synthesis and release, tryyodotyroninu (T3) and thyroxine (T4) in  the application Sodium  Nitroprusside alpha-tyreotropinu 0.9 mg TSH stimulation of hormones needed  for diagnostic procedures, achieved here  a background therapy, which provides normal thyroid function, reducing the level  of thyroid hormone, thus avoiding symptoms spunkiness to deficiency of thyroid  function. Indications for use drugs: treatment of patients with acromegaly, in  spunkiness surgery and / or radiation therapy had no effect, and the appropriate  therapeutic treatment of somatostatin analogs did not lead spunkiness  normalization of concentrations of insulin growth factor-1 (IFR-1) or postponed  Hairy Cell  Leukemia spunkiness . 
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