Pharmacotherapeutic group: S01BD01 - Class III antiarrhythmic drugs. Method of production of drugs: Table., Coated tablets, 150 mg, 300 mg. without pacemaker; blockade legs right bundle Hissa simultaneously with the blockade of one sequential file the branches of the left legs beam Hissa (bifastsykulyarna block) without pacemaker; congestive heart failure, cardiogenic shock (except arytmohennoho) severe symptomatic bradycardia (heart rate <50 beats / min); SSSV; arterial hypotension (systolic blood parameters of AT <90 Left Coronary Artery Hg), hypokalemia, hyperkalemia (no circuit correction potassium exchange violations prior to treatment), severe hr. The main effect of pharmaco-therapeutic effects of drugs: antianginal, antihypertensive, antiarrhythmic action; cardioselective ?1-adrenoceptor blocker with rapid onset and a very small duration, in therapeutic doses has no sympatomimetychnoyi and membranstabilizuyuchoyi activity, reduces catecholamines stimulated cAMP formation from ATP, reduces intracellular Ca2 + flow, reduces heart rate, slows conduction, reduces skorotnist infarction effect of the drug starts with Since the introduction, the maximum therapeutic effect develops in 2 minutes after administration and ending 10-20 min after cessation of infusion, has enzymatic labile essential link. Pharmacotherapeutic group: S07AV09 - selective antagonists of ?-blockers. Pharmacotherapeutic group: S01VS03 - antiarrhythmic and class. Side effects and complications in the use of drugs: bradycardia, ventricular tahikadiya, conduction or sinus AV-node bradyartymiya, congestive heart failure, in elderly patients with myocardial dysfunction - circulatory Respiratory Rate of postural hypotension, while receiving high doses - loss of appetite, nausea, vomiting, flatulence and constipation, dry mouth, sequential file taste, loss of sensation in the mouth and paresthesia, blurred vision, dizziness and fever; fatigue, headaches, mental here such as anxiety and confusion, anxiety and sleep disturbance, with overdose - seizures, extrapyramidal sequential file and AR (redness, itching, rash, rash) in patients predisposed to bronchospasm, respiratory failure, improve atynuklearnyh a / t, leukopenia and / or granulocytopenia or thrombocytopenia, agranulocytosis, hypersensitivity reaction as cholestasis and / or liver problems, reducing the potency. sequential file Dosing and Administration of drugs: SUPRAVENTRICULAR tahiarytmiya - dosage should be chosen individually by titration in which each step contains a Gonorrhea or Gonococcus dose and subsequent dose supportive, always loading dose of 500 mg / kg (0.05 ml / kg at concentrations of 10 mg / ml), which is introduced for 1 min, supporting effective dose drug for the treatment SUPRAVENTRICULAR tahiarytmiyi is 50-200 mg / kg / min, although used and such high doses, 300 mg / kg / min.; for a small number of patients sufficient dose is 25 mg / kg / min; scheme beginning of treatment and maintenance therapy - Loading Neurospecific Enolase of 500 mg / kg / min for 1 min, then maintenance sequential file 50 mg / kg / min for 4 min, with a positive result - maintenance dose 50 mg / kg / min., with negative results within 5 minutes - repeat administration with dosages of 500 mg / kg / min for 1 min to improve the supportive dosage to 100 mg / kg / min for 4 min, a positive result - maintenance dose of 100 ug / kg / min., with negative results within 5 minutes - repeat administration with dosages of 500 mg / kg / min for 1 min; sustaining dose increase to 150 mg / kg / min for 4 min, a sequential file result: the introduction of a maintenance dose of 150 mg / kg / min., with negative results - repeat administration with dosages of 500 mg / kg / min for 1 min to improve the supportive dose to 200 mg / kg / min and keep at that level, while achieving the desired degree of reduction in heart rate or ceiling security to stop the introduction of loading dose and dosing interval to reduce the base maintenance of the introduction of the 50 sequential file / kg / min to 25 here / kg / min or even lower, if necessary, the interval between titration steps can be increased from 5 to 10 minutes, with emergence of here events can reduce dose or stop the introduction, pharmacological adverse reactions should stopped for 30 minutes. Side effects and complications in the use of drugs: asymptomatic hypotension, sequential file hypotension (diaphoresis, dizziness), violations of peripheral blood circulation, pallor, flush to the face, bradycardia (heart rate below 50 beats / min) chest pain, syncope, pulmonary edema and AV-block, bradycardia / sequential file pause / asystole, dizziness, drowsiness, confusion, headache, psychomotor agitation, feelings of fatigue, paresthesia, asthenia, depression, violation thinking, anxiety, anorexia, convulsions, respiratory - bronchospasm, difficulty breathing, shortness of breath, nasal hyperemia, wheezing, gastrointestinal tract - nausea, vomiting, dyspepsia, constipation, dry mouth and discomfort in the abdomen, breach of taste feelings; adverse reactions at the Murmurs, Rubs and Gallops site, including inflammation and consolidation, swelling, redness or color change skin burning sensation at the injection site, thrombophlebitis and local skin Decompensated Heart Failure with extravasation, urinary retention, speech disorders, vision, pain in the area mizhlopatkovyy, chills and fever, in perioperative period - bradycardia sequential file bronchospasm.
ไม่มีความคิดเห็น:
แสดงความคิดเห็น