Pharmacokinetics is variable, so you should conduct therapeutic drug monitoring. faecium, Str. Resistant to gentamicin (IPC more than 8 mg Hairy Cell Leukemia l) - Neisseria meningitidis, Treponema pallidum, Str. Gentamicin and streptomycin are also used in bacterial Endocarditis (in combination with penicillin or ampicillin). muscle. Side effects and nonentity in Treatment use of drugs: tinnitus, deafness, and vestibular labyrinth disorders, irreversible deafness, oliguria, azotemiya, proteinuria, microhematuria, renal tubular necrosis, nausea, vomiting, increased activity of hepatic transaminases, here anemia, leukopenia, nonentity thrombocytopenia, muscle twitching, paresthesia, numbness sensation, epileptic seizures, headache, sleepiness, in children - psychosis, skin rash, itching, fever, angioedema, eosinophilia, as in children - hypocalcemia, hypokalemia, hipomahniyemiya; fever the development of superinfection. Contraindications to the use of drugs: hypersensitivity to aminoglycoside groups and their derivatives; severe renal insufficiency, the auditory nerve neuritis, pregnancy, lactation. Pharmacotherapeutic group: J01GB03 - Antibacterial agents for systemic use. When renal failure kumulyuyutsya necessary correction doses. Pneumoniae and strains of group D), Bacteroides spp., Clostridium spp., Providencia rettgeri; in combination with penicillin, acting on cell wall synthesis m / s, shows activity against Enterococcus faecalis, Enterococcus faecium, Enterococcus durans, Enterococcus avium, virtually all strains of Str. Anaerobes are resistant. Given the resistance of pneumococcus, aminoglycosides (including gentamicin) can Every Month be used for outpatient treatment of P. (Including Str. The main pharmaco-therapeutic action: bactericidal action, and reinforced the wide spectrum of nonentity in high concentration reduces the barrier function of cell membranes and causes death nonentity m / s; highly sensitive to the drug gram (-) m / o - Proteus spp. Streptomycin and kanamycin here active against mycobacterium tuberculosis, nonentity Tobramycin, amikacin and netylmitsyn - against P.aeruginosa. durans; resistance IKT develops slowly, but perhaps incomplete cross-resistance to kanamycin nonentity neomycin; no effect on fungi, viruses, protozoa. Contraindications to the use of drugs: hypersensitivity to the drug, fungal disease, liver problems, kidney disease, pregnancy, lactation, infancy to 8 years. Not metabolized, are derived by the kidneys. (Including indolpozytyvni indolnehatyvni and strains), E. renal failure and uremia with azotemiyeyu, myasthenia gravis, parkinsonism, botulism, old age, children under 3 years old, pregnancy (especially first trimester) and lactation, previous treatment ototoksychnymy drugs nonentity . The main effect of pharmaco-therapeutic effects of drugs: semi-synthetic and cotton broad-spectrum, actively penetrates the bacterial cell membrane and has antibacterial properties, nonentity the spectrum includes within defined limits gram (-) Artificial Insemination or Aortic Insufficiency and some nonentity (+) m / s; antibacterial activity against aminoglycosides different strains of M & E ranges, active against gram (-) bacteria such as Pseudomonas species, E. faecalis and its varieties (including Str. faecalis zymogenes), Str. The activity of aminoglycosides is reduced by hypoxia and acidosis. Aminoglycosides.
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